Klin Farmakol Farm. 2006;20(3):135-139

QUALITY INDICATORS OF PHARMACOTHERAPY IN GERIATRICS

Martin Wawruch5, Tatiana Foltánová1, Martina Žikavská5, Magdaléna Kuželová1, doc. MUDr. Pavel Weber CSc2, Jana Tisoňová5, Beáta Mladosievičová3, Peter Krutý4, Milan Kriška5,6
1 Katedra farmakológie a toxikológie, Farmaceutická fakulta UK, Bratislava
2 klinika geriatrie FN, Brno
3 Ústav patologickej fyziológie, Považská Bystrica
4 -
5 Farmakologický ústav Lekárskej fakulty UK, Bratislava
6 Nemocnica s poliklinikou Považská Bystrica

The improvement of the health care quality represents a common goal of professionals at different levels of health care and a prominent public priority. The inseparable part of the health care is pharmacotherapy. The unbiased comparison and evaluation of trends of pharmacotherapy quality require a quantitative analysis using quality indicators. Quality indicator is defined as a measurable element of prescribing performance for which there is evidence or consensus that it can be used to assess quality, and hence in changing the quality of care provided. They can be classified according to their focus (structure, process and outcome indicators) and their content (drug, disease and patient oriented indicators). Optimal indicators are based on the evidence–based medicine. In cases, when there is little evidence to draw unequivocal recommendations, the indicators based on combination of evidence and expert opinion consensus are used (Delphi technique, RAND appropriateness method). The development and opinion on the relevance of quality indicators are still in progress. They are used in descriptive assessment of pharmacotherapy and as a tool for improvement of its quality. The aim of the article was to provide information about this developing topic and to describe an example on their application in the practice. For example we provide an evaluation of a group of 600 patients aged ≥ 65 years from the point of view of potentially inappropriate drug use in elderly. Inappropriate drugs were defined by modified Beers 2003 criteria that were created by Delphi technique. In the evaluated group at least one potentially inappropriate drug occurred in 121 (20.2 %) and 120 (20 %) patients at the time of hospital admission and discharge, respectively.

Keywords: Key words: quality indicators, classification, pharmacotherapy, elderly patients, potentially inappropriate medication.

Published: January 1, 2007  Show citation

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Wawruch M, Foltánová T, Žikavská M, Kuželová M, Weber P, Tisoňová J, et al.. QUALITY INDICATORS OF PHARMACOTHERAPY IN GERIATRICS. Klin Farmakol Farm. 2006;20(3):135-139.
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References

  1. Hoven JL, Haaijer-Ruskamp FM, Vander Stichele RH. Indicators of prescribing quality in drug utilisation research: report of a European meeting (DURQUIM, 13-15 May 2004) Eur J Clin Pharmacol 2005;60:831-834. Go to original source... Go to PubMed...
  2. Barber N. What constitutes good prescribing? BMJ 1995;310:923. Go to original source... Go to PubMed...
  3. Lawrence M, Olesen F. Indicators of quality of health care. Eur J Gen Pract 1997;3:103-108. Go to original source...
  4. Campbell SM, Cantrill JA, Roberts D. Prescribing indicators for UK general practice: Delphi consultation study. BMJ 2000;321:425-428. Go to original source... Go to PubMed...
  5. Luthi JC, Burnand B, McClellan WM, Pitts SR, Flanders WD. Is readmission to hospital an indicator of poor process of care for patients with heart failure? Qual Saf Health Care 2004;13:46-51. Go to original source... Go to PubMed...
  6. Campbell SM, Braspenning J, Hutchinson A, Marshall M. Research methods used in developing and applying quality indicators in primary care. Qual Saf Health Care 2002;11:358-364. Go to original source... Go to PubMed...
  7. Campbell SM, Braspenning J, Hutchinson A, Marshall MN. Research methods used in developing and applying quality indicators in primary care. BMJ 2003;326:816-819. Go to original source... Go to PubMed...
  8. Bergman U, Popa C, Tomson Y et al. Drug utilization 90% - a simple method for assessing the quality of drug prescribing. Eur J Clin Pharmacol 1998;54:113-118. Go to original source... Go to PubMed...
  9. van Dijk KN, Pont LG, de Vries CS, Franken M, Brouwers JRB, de Jong-van den Berg LTW. Prescribing indicators for evaluating drug use in nursing homes. Ann Pharmacother 2003;37:1136-1141. Go to original source... Go to PubMed...
  10. Wettermark B, Pehrsson A, Jinnerot D, Bergman U. Drug utilisation 90% profiles - a useful tool for quality assessment of prescribing in primary health care in Stockholm. Pharmacoepidemiol Drug Saf 2003;12:499-510. Go to original source... Go to PubMed...
  11. Pont LG, van Gilst WH, Lok DJA, Kragten HJA, Haaijer-Ruskamp FM. The relevance of heart failure severity for treatment with evidence-based pharmacotherapy in general practice. Eur J Heart Fail 2003;5:187-193. Go to original source... Go to PubMed...
  12. ATC index with DDDs. Oslo: WHO Collaborating Centre for Drug Statistics Methodology, 2000:179.
  13. Engels Y, Campbell SM, Dautzenberg M et al. Developing a framework of, and quality indicators for, general practice management in Europe. Fam Pract 2005;22:215-222. Go to original source... Go to PubMed...
  14. Steel N, Melzer D, Shekelle PG, Wenger NS, Forsyth D, McWilliams BC. Developing quality indicators for older adults: transfer from the USA to the UK is feasible. Qual Saf Health Care 2004;13:260-264. Go to original source... Go to PubMed...
  15. Campbell SM, Shield T, Rogers A, Gask L. How do stakeholder groups vary in a Delphi technique about primary mental health care and what factors influence their ratings? Qual Saf Health Care 2004;13:428-434. Go to original source... Go to PubMed...
  16. Gagliardi AR, Fung MFK, Langer B, Stern H, Brown AD. Development of ovarian cancer surgery quality indicators using a modified Delphi approach. Gynecol Oncol 2005;97:446-456. Go to original source... Go to PubMed...
  17. Gagliardi AR, Simunovic M, Langer B, Stern H, Brown AD. Development of quality indicators for colorectal cancer surgery, using a 3-step modified Delphi approach. Can J Surg 2005;48:441-452.
  18. Normand SL, McNeil BJ, Peterson LE, Palmer RH. Eliciting expert opinion using the Delphi technique: identifying performance indicators for cardiovascular disease. Int J Qual Helath Care 1998;10:247-260. Go to original source... Go to PubMed...
  19. Fick DM, Cooper JW, Wade WE, Waller JL, Maclean JR, Beers MH. Updating the Beers criteria for potentially inappropriate medication use in older adults. Arch Intern Med 2003;163:2716-2724. Go to original source... Go to PubMed...
  20. Campbell SM, Hann M, Hacker J, Durie A, Thapar A, Roland MO. Quality assessment for three common conditions in primary care: validity and reliability of review criteria developed by expert panels for angina, asthma and type 2 diabetes. Qual Saf Health Care 2002b;11 (2):125-130. Go to original source... Go to PubMed...
  21. Hemingway H, Crook AM, Feder G et al. Underuse of coronary revascularization procedures in patients considered appropriate candidates for revascularization. N Engl J Med 2001;344:645-654. Go to original source... Go to PubMed...
  22. Shekelle PG, MacLean CH, Morton SC, Wenger NS. Assessing care of vulnerable elders: methods for developing quality indicators. Ann Intern Med 2001;135:647-652. Go to original source... Go to PubMed...
  23. Baker R. Managing quality in primary health care: the need for valid information about performance. Qual Helath Care 2000;9:83. Go to original source... Go to PubMed...
  24. Wilkinson EK, McColl A, Exworthy M et al. Reactions to the use of evidence-based performance indicators in primary care: a qualitative study. Qual Health Care 2000;9:166-174. Go to original source... Go to PubMed...
  25. Kirk SA, Campbell SM, Kennell-Webb S, Reeves D, Ronald MO, Marshall MN. Assessing the quality of care of multiple conditions in general practice: practical and methodological problems. Qual Saf Health Care 2003;12:421-427. Go to original source... Go to PubMed...
  26. Garcia Rodriguez LA, Perez Gutthann S. Use of the UK General Practice Research Database for pharmacoepidemiology. Br J Clin Pharmacol 1998;45:419-425. Go to original source... Go to PubMed...
  27. Wawruch M, Weber P, Kuželová M et al. Riziko liekov v geriatrii. Interná Medicína 2006;5:101-106.
  28. Fialová D, Topinková E. Koncept léčiv nevhodných ve stáří - farmakologické a farmakoepidemiologické aspekty. Remedia 2005;15:410-417.
  29. Beers MH, Ouslander JG, Rollingher I, Reuben DB, Brooks J, Beck JC. Explicit criteria for determining inappropriate medication use in nursing home residents. Arch Intern Med 1991;151:1825-1832. Go to original source...
  30. Beers MH. Exciplit criteria for determining inapprotiate medication use by the elderly. Arch Intern Med 1997;157:1531-1536. Go to original source...
  31. Fialova D, Topinkova E, Gambassi G et al. Potentially inappropriate medication use among elderly home care patients in Europe. JAMA 2005;293:1348-1358. Go to original source... Go to PubMed...
  32. Onder G, Landi F, Liperoti R, Fialova D, Gambassi G, Bernabei R. Impact of inappropriate drug use among hospitalized older adults. Eur J Clin Pharmacol 2005;61:453-459. Go to original source... Go to PubMed...
  33. McLeod PJ, Huang AR, Tamblyn RM, Gayton DC. Defining inappropriate practices in prescribing for elderly people:a national consensus panel. CMAJ 1997;156:385-391. Go to PubMed...
  34. Solomon DH, Wenger NS, Saliba D, Young RT et al. Appropriateness of quality indicators for older patients with advanced dementia and poor prognosis. J Am Geriatr Soc 2003;51:902-907. Go to original source... Go to PubMed...




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