Klin Farmakol Farm. 2019;33(4):30-34 | DOI: 10.36290/far.2019.029

Risk minimization and three pillar theory for drugs that inerease the risk of falls

Jiří Vlček¹, Sylva Bártlová², Iva Brabcová², Martin Doseděl¹, Hana Hajduchová², Aleš Kuběna¹, Josef Malý¹, Valérie Tóthová², Jan Vosátka¹

¹ Univerzita Karlova, Farmaceutická fakulta v Hradci Králové, Katedra sociální a klinické farmacie

² Jihočeská Univerzita v Českých Budějovicích, Zdravotně sociální fakulta

Falls are adverse events and they can do a harm of patients. Falls are more risky for elderly and about 25 % of visitors to emergency department are as a result of the fall and about one quarter of them are admitted to the medical ward. Fall is an multifactorial event and there are many risk factors influenceable and non-influenceable, internal and external ones. Medicine are part of influenceable risk factors. The goal is to introduce general view on risk minimization management, to explain theory of three pillars in relationship to medicines with fall potential and to of fall and to identify their risk factors. We linked falls to different types of ADR according WHO classification and focussed on medicine specific risk factors of falls. We analysed medicine causing vertigo, confusing, changes of sensoric organs and another pathophysiologic changes to participate in drug related fall. We applied three pillars theory for it.

Conclusions: Specialist for drug related problems needs to know good theory of three pillars of ADR. Good knowledge about pathophysiology of falls and way which tool of drug use is necessary to understand to minimize risk of fall as well. This knowledge can be useful and used for risk minimization algorithm SAFE

Keywords: fall, risk minimization, FRID, drug related problem, theory of three pillars, adverse drug reaction, medicine related risk factors.

Published: January 1, 2020  Show citation