Klin Farmakol Farm. 2019;33(3):37-40 | DOI: 10.36290/far.2019.021

Future trends in esophageal cancer treatment (prevention, biological therapy, immunotherapy, individualized therapy, novelties in surgery)

Zuzana Rábeková

Klinika hepatogastroenterologie, Institut klinické a experimentální medicíny, Praha

Esophageal carcinoma may be devided into two most frequent histopathological subtypes – adenocarcinoma and squamous cell carcinoma, which are different in their origin and biological characteristic, but also in their response to different types of the treatment. Esophageal cancer is the 8th most common maligncy and 6th most common cause of death from overall malignant disease. Searching for novel and effective methods in its prevention and treatment is very important issue, according to very low 5 – years survival rate, which is between 15–20%. The future may bring novelties in prevention of this tumor as in the area of chemoprotective substancies, as in new endoscopic or surgical antireflux modalities; news in biological treatment, imunotherapy and individualized therapy or in surgical approach.

Keywords: esophageal carcinoma, antireflux therapy, biological therapy, immune therapy, individualized therapy

Published: October 28, 2019  Show citation