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KLINICKÁ341804001074588109168189242288347
FARMAKOLOGIE709804001074291138211265312372415474533554598
A13288040010753
FARMACIE1403804001074191138210265316336380
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Klin190680400107446583131
Farmakol2057804001074278105179220258305325
Farm.2402804001074178104179195
2026;40(2):108-1112617804001074487128170185229275299342364379416455500529567602636
/32988040010732
www.klinickafarmakologie.cz4568804001076513320121425327329234035839843647950254457164568672477179183988990895196610061045
1081288020012657111170
HLAVNÍ341200012670127198263336370
TÉMA733200012657114204274
Environmental34136001063071110127162203245299330372404440471
sustainability82836001063171103136172189231270306324355373405444
in128836001061556
clinical13603600106326481122140174216247
research162336001063365100131173208243284
Environmental3399200298128268389453543680819102311491289137415001564
sustainability19529200298104242344431558621760884102610911155121813041433
in3434920029865204
clinical36879200298108173237376439546671736
research4471920029891217320445571660767907
Michaela3391320013793124173238296354385443
Beníšková1,8041320013767125190220269329391448506130213300803613371320013729
Jitka1388132001374575116176235
Rychlíčková1,16451320013765124172237267297346406468525583222013300803651
22284133008036
1Department3391480078333691480013373129191244280319410465526561
of953148001336192
Pharmacology,10691480013358117170205297349398456482543605657674
Faculty17661480013354102151211236272326
of2116148001336091
Medicine,22311480013388144206231280305365420442
Masaryk26961480013388141184237272327379
University,30991480013371131156208262298341366402456474
Brno3596148001336095156216
2St.339163007833373163001335488111
Anne’s5071630013368128188243266305
University8361630013371131156208262298342366402457
Hospital13161630013372132175237262298351377
Brno1716163001336095156216
Greenhouse339214001216599150202258315371427467518
gases8822140012155105145196237
have11432140012155104152202
a13692140012148
significant1441214001214064121177201231259304354410444
impact19092140012123107165215260297
on22302140012155111
the2366214001213389140
global2530214001215681137195245269
climate.282321400121456993177226260310331
The31782140012150107159
healthcare33612140012156107156180214271317366400450
sector339228001214091138174229263
is627228001212363
one7152280012155111163
of903228001215585
the1012228001213390141
main11782280012183132157213
sources1416228001213995152185230280321
of1762228001215585
CO₂18722280012158124157
emissions.20542280012150135159199239263319375415438
Globally,2516228001216590147205254279303351368
it2909228001212458
represents2992228001213283141175226266318374408449
the3466228001213389141
fifth363222800121295686124180
largest339242001212473106163214255289
source.654242001213995152185230280302
Clinical981242001215882106162186232281306
research1312242001213283124175224258303359
is1696242001212463
an17852420012148104
integral1914242001212480113163221255304329
part22682420012157107140177
of2470242001215585
this2580242001213390114153
sector;2759242001213991137174229263285
it3069242001212458
drives3152242001215690114164214254
innovation,34312420012124801361922412903243483392560012155112133
but4952560012157114148
also666256001214872112168
places857256001215782131177227268
an11482560012148104
additional12752560012148106164188222246302359408432
burden17302560012157113147204255312
on20652560012155112
the2200256001213389140
environment.23632560012150107154179213268325409461517551573
Therefore,29592560012150107158192243274330364415435
efforts3417256001215181115171205242283
to3723256001213388
minimize3392700012183108164188272296340391
the759270001213389141
carbon928270001214595128186243300
footprint1257270001212985142175233267292348381
are1667270001214882132
also1828270001214873112169
permeating20252700012157109143228280329362386443500
the2553270001213390141
methodology27232700012183135169225281340396421477535584
and33352700012148105162
design35262700012156108148172229286
of339284001215585
clinical44728400121456993149173219269293
trials76328400121336791140165204
as991284001214888
well11022840012174124149173
as1299284001214888
clinical141028400121456993149173219268293
research1726284001213384124176225258303359
in2109284001212379
general.22112840012156108164216250299324345
Digitization339298001216690145169202225268317350373428483
and8412980012148103159
decentralization10192980012155105151200255288320369392415458508540563618674
of1711298001215484
clinical181329800121446891146169214262286
trials211829800121326589136160199
can2335298001214493148
help25022980012154105129185
to2706298001213286
reduce2811298001213282139193238287
the3117298001213287137
environmental32732980012149105151175208262317400450506339312001213382107
burden.4653120012157113146203254310332
However,8173120012165121194245293343376393
these1230312001213388140180231
benefits14813120012156108164215246273307348
remain1849312001213283167215239295
largely2164312001212372105161212237285
hypothetical24693120012155101160216250306357391415460509533
now30223120012155111185
due32263120012156112163
to3408312001213388
limited3516312001212347131155188238296
supporting339326001214095153211268302339363419476
data.8353260012157106139189211
In1066326001212481
order1167326001215589146197231
to1419326001213388
develop15273260012156108156206231287346
more18933260012183139173224
sustainable2137326001214095135170220244300349407432484
clinical264132600121456993149173219268293
trial295432600121336791140164
methodologies,31393260012183135169225281340396421477535559610651673
it339340001212358
is417340001212463
necessary5013400012156107154204244285335368419
to941340001213388
quantify10503400012156112161217251275305357
emissions14283400012150134159198238262318375415
in1864340001212379
clinical196434000121456993149173219269293
research2278340001213283124175224258303359
more26583400012183139173224
precisely2903340001215791142188212252303328377
and33013400012148104162
identify3484340001212380132188222246276328
key339354001214797145
areas507354001214881132181221
for751354001213086120
reducing894354001213283142197243267323380
emissions12983540012150134159198238262318375415
in1736354001212380
clinical183935400121456993149173219268293
research.2155354001213383124175224258303359381
This3393680012150109134174
article544368001214984121146193218270
aims845368001214974159200
to1076368001213490
raise1197368001213384109149202
awareness14303680012149124174209260318371412453
of1914368001215687
sustainable2032368001214097138173224249306356415441493
clinical255636800121467195153177224275300
research2887368001213385126179229263310367
and32853680012149106165
present3481368001215893144186238296330
relevant339382001213383108160208258314348
initiatives710382001212379103137161210244268317367408
and11413820012148104162
activities.1326382001214894130154204229263287338378401
Key3393980012461113164
words:5243980012476133171231275301
sustainability,846399001214094133167216239294342399422446469502552568
clinical143539900121456891146169214262286
trials,174239900121336689137160199220
healthcare,19833990012156106154178211266311360392442462
clinical246639900121456891146169214262286
research,2773399001213383122173221253297352373
education.31673990012150108162207256288311366422443
Environmentální3394260012453113164192231289348434487547583637665724752
udržitelnost11114260012458118157205233270324352411469512550
v16814260012453
klinickém1754426001245483111170198243298350437
výzkumu22114260012453108157213272358417
Skleníkové339444001214995120171226249297351398447
plyny804444001215680127184229
zásadně1051444001214292131180236291341
ovlivňují14104440012155102126149197253307331354
globální1781444001215679134191240263318341
klima.214044400121477194177225246
Sektor2404444001214999146182236269
zdravotní2690444001214399132180226280313368391
péče30994440012156107153201
představuje3318444001215790139196235269317364419443493
jeden339458001212475132182238
z5974580012142
významných659458001214899144199247330386431475530
zdrojů1209458001214399132186210264
emisí14934580012150134157196219
CO₂,17324580012158123155178
v19304580012148
celosvětovém1997458001214594118173213262311344398445494578
měřítku25944580012184134166190223269324
se2938458001214090
řadí3048458001213381138161
na32294580012155103
páté33524580012157105138187
místo.35594580012183107145179233252
Klinický339472001215479102157180225271322
výzkum681472001214899144191246329
je1031472001212474
jeho1126472001212474130185
nedílnou13324720012155106163186211267322377
součástí;1729472001214095150195244283317340359
přináší2108472001215790114169217256279
inovace,2407472001212479134181230274323343
ale2771472001214871122
i29134720012123
další29574720012156104128166189
environmentální31674720012150106152176208263319402452508540589612339486001215679
zátěž.446486001214393125174218239
Snaha7134860012150105153208256
minimalizovat9974860012184107163186269317341364407461508557590
uhlíkovou16154860012155110134157206259307361416
stopu2059486001214074128185241
proto2328486001215790145178232
prostupuje2588486001215790145184218273330385409459
i30764860012123
do31274860012157112
metodologie32674860012184134168222279334359414471494544
a3395000012148
designu4085000012157107147169225281335
klinických76550000121477295150173218264314358413
studií1199500001214074129185208232
a14525000012148
klinického152150000121477295150173218264313369424
výzkumu1966500001214999144191247330385
jako2372500001212472119172
celku.2566500001214493117164219240
Prvky339514001215385136183234
jako594514001212472119173
digitalizace788514001215780136159192241264287330380425474
a12835140012148
decentralizace13535140012156106152201257289322370394417459509554603
klinických197751400121477295150173218265315359414
studií2412514001214074129185208231
mohou26655140012183138194249305
přispět2991514001215790113152209260293
ke3305514001214796
snižování3423514001213994117160214262310365388
environmentální3395280012150105151175207261316399449504536585608662685
zátěže.1042528001214292124173215265285
Stále1344528001214980129152202
jde1563528001212581131
ale1711528001214871121
spíše1850528001213995119159209
o20775280012155
předpoklad2149528001215789138195252307354379426482
podložený26495280012157112169192247288338393438
omezenými31055280012154138188231280335381464487
daty.36105280012156104136185201
K3395420012156
dosažení4185420012158116157208254306364389
udržitelnějších8395420012156116150197221256308333391443469509534581638
metodik15095420012186139175231291315364
je1905542001212578
třeba2015542001213468120180231
cílenější227854200121467198150208261286327352
kvantifikace26625420012148102152210244269300327376428475526
a32205420012150
identifikace3302542001212483136194228253284311360412459510
klíčových33955600121477295139193240291335390
oblastí7505560012155112136184223257280
pro1051556001215790144
redukci1217556001213282139194241284307
emisí15465560012150133156195218
v17855560012149
klinickém185555600121477295150173218264313397
výzkumu.2273556001214898144190246329384405
Článek339570001215880128182232279
si636570001213962
klade715570001214771119175225
za957570001214392
cíl106757000121446792
zviditelnit1176570001214393117173196228277301355378411
problematiku1604570001215789143200224274357404436459505560
udržitelného21825700012154110143187210242291315369419475529
klinického272957000121467194148171215261310365420
výzkumu,3166570001214898143189244327381401
představit3585570001215689138195339584001214073122169193226
iniciativy586584001212379102146169217250273321372
a9795840012148
aktivity1048584001214895131154202226259309
v13785840012148
této1448584001213382115169
oblasti.16395840012154112136184223256280300
Klíčová339600001246189116160217268320
slova:675600001244371128179231256
udržitelnost,9476010012155110142186209241289313367421460493513
klinické147760100121477194148170214260308
studie,1802601001213972126182205254273
zdravotnictví,2092601001214398130178223276309363385429464514537557
klinický266660100121467193147170214259309
výzkum,2992601001214897142188242324344
vzdělávání.3354601001214791147196219266312360414437457
Does3396470014782151214264
sustainable6316470014750118168212274305374435506538600
healthcare3396610014769131193224266335390452495557
matter?92466100147101163205250311355400
The479678001094597144
global650678001095173124177222245
healthcare922678001095097142164195246288334364410
sector1360678001093582125158208239
has1626678001095095132
emerged17856780010945122169200339692001095198152
as519692001094380
a6276920010944
significant699692001093658111163185213238281326378409
contributor1136692001094191143174205228281333365415447
to1611692001093080
anthropogenic17196920010944961271782092603397060010951103155202253275317
climate68370600109406384161205236282
change.992706001094091135186238285304
Current13247060010952101132163209260291
estimates1642706001094582113136212256287333369
indicate339720001092172124146188233263309
that671720001093080125155
it849720001092152
represents924720001092975128159205242289340370408
1–5%1355720001094689135206
of1584720001094977
the1683720001093081128
total1833720001093080111156178
impact339734001092196147191232264
on620734001094999
climate73673400109406283158202231276
change,1029734001094090133183234280298
producing1344734001095181130182232273294344395
approximately1756734001094394146176225339748001094163138181211256278321
2.0–2.6677748001094665112160203222269
billion96374800109517394116137187237
tons1217748001092978129164
of1398748001094975
CO2149074800109521111599754006427
emissions16437480010944120141176212233283333369
globally339762001095071121173217238260303
per659762001095096126
year802762001094287130160
corresponding979762001094088118148193229280331381432454504554
to1550762001093078
4.4–5%1645762001094665111159205274
of1936762001094975
the339776001093081127
global488776001095072123176221244
greenhouse753776001095081127174226277327379415462
gas1236776001095095131
emissions.13897760010945121144180216238289340377397
Thus,1807776001094597148184204
the2139650001093081127
healthcare2287650001095097141164195246287332363409
sector2717650001093582124157207238
ranks2976650001093075125169208
fifth320565000109265179113164
among33896500010944120171222274
the3684650001093081127
largest2139664001092268100154202241274
CO2244266400109541172558670006428
producers.2614664001095385138193245289336368408429
The30726640010946100149
production3250664001095385138193245289323347399453
of3732664001095180
CO2213967800109521122249684006427
emissions22936780010945121142178214236286337372
contributes2683678001094089140170200222274325355400437
to3137678001093079
climate323467800109406283159203233278
change3529678001094091135185236282
and2139692001094393144
health2299692001095095139160190240
issues255669200109205691140186222
or2794692001094979
deaths2890692001095095139168218253
related316069200109297496140169214265
to3442692001092978
climate353769200109406182157200230274
change2139706001094091136187238285
(often2443706001092674101135181232
expressed2694706001094689142173219256292339392
in3105706001092172
disability-adjusted31977060010950731091542062292512733043503804244764995505862139720001092973125
life228072000109214268113
years2410720001094186129158194
–26217200010944
DALYs).26817200010959111153195226248265
Treating2963720001094468113156185206256306
them3285720001093079124198
imposes3500720001092195145195231276312
monetary21397340010977129182230262309340388
costs2556734001094192130162201
for2786734001092679111
the2925734001093083131
healthcare3084734001095199145168200252295342373421
system3533734001093682120153200278
and2139748001094392143
simultaneously2299748001093556131180202232276326371421471506528571
generates2887748001094994145190220264293338374
additional3278748001094293144165196217266316360381
CO2367674800109521113785754006426
emissions.21397620010946124147184222245297350387408
This2575762001094699122159
creates2763762001094172119165197243281
a30737620010944
downward31457620010952104173226294340371424
spiral3598762001093689113144190214
and2139776001094495148
is2314776001092158
precisely2399776001095283130172194231278301345
why27727760010967118161
healthcare2961776001095097142164196247289334365411
represents3400776001093076129160207244291343373411
DECLARATIONS:4068216008648871301662142563043393604124625014570216008514
Declaration406823000874987120141179206244271291333375
of445723000874066
originality:45372300087406888130150192230251271298337356
The406824100853473109
manuscript418824100855891130168195227249266306329
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and481624100853472112
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Ethical406826600873764107127160198218
principles43002660087427090132165185228249287319
compliance:463326600873173134177197218256298330368387
The406827700853678116
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attest44642770085356087124153179
that466427700852465101126
their481127700852465103121146
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by406828800854073
the41582880085236399
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Committee464828800854179139198215239265300337
and500228800853373113
is513228800851745
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Medical427332100855795137155188224242
Association453532100854474104144178196231256273314355
Declaration491132100854785119136172196232257274315356
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Helsinki537032100854684102131149189224243
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Ethical41653320085355898115147182199
Principles43833320085376178117150167207225261290
for46923320085205983
Medical479433200855693134151183218235
Research504833200853874102139173197229268
Involving53353320085175690128146181198238278
Human406834300854685145179219
Subjects430734300853474114132168201227256
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