119
www.klinickafarmakologie.cz340804301076513320121425327329234035839843647950254457164568672477179183988990895196610061045
/26548043010757
Klin2730804301077091109157
Farmakol2907804301074279105179220258305325
Farm3252804301074178105179
2022;36(3):85-923451804301074487128172187231275298341362376420463491535577
/40478043010777
KLINICKÁ41438043010772115136195216269315373
FARMAKOLOGIE4537804301074292139211266313373415475534555599
A51568043010754
FARMACIE5230804301074392140212267318338382
8956558026012657115
Fig.34062301124771125149
2.50762301125075
Bland-Altman62862801074362107153198225274293318390435481
analysis112562801074592137155192223240270
of141162801074568
measured1495628010771110155185229255291337
and184862801074592137
predicted200162801074571108154172209237273319
vancomycin233662801073882128165209280316353371417
concentrations276962801073781127164201247272298341366384430476506
by329162801074581
(A)33886280107247295
WIN1,349962801077391146183194
(B)37096280107246689
WIN2,381462801077391146186200
(C)40306280107247195
WIN3,414162801077391146185201
(D)435862801072479101
WIN4,447662801077290145186202
(E)46946280107246286
DOS1.4796628010757116153189201
(F)50136280107246286
DOS25115628010757115153193
(A)1906229101122887115
(D)1906400701122888115
(B)3550229101122882109
(E)3550400701122876104
(C)5336229101122880109
(F)5336400701122875103
Fig.340442301124771125149
3.507442301125377
Comparison629442801074891163209254280298328372419
of1064442801074770
vancomycin1150442801074184131168211283318355373419
concentrations1586442801073983129166203249274300343368386432478508
predicted2110442801074874110156174212239276321
by2447442801074884
DOS125474428010759118156191
and2754442801074894140
predicted2910442801074773110156174211239275321
by3247442801074884
(A)334744280107267497
WIN13460442801077593148185
model,36614428010774119166204222238
(B)391544280107266891
WIN24022442801077593148188
model,42264428010774119165204222237
(C)448044280107267397
WIN34593442801077593148187
model,47964428010774119165204222237
(D)5050442801072681104
WIN45170442801077593148189
model,53754428010774119165203222237
(E)34045380107246286
DOS14424538010757116153189
model.6474538010771117163201219236
The899453801073987125
full104045380107236988106
line116245380107193783121
represents1299453801072663109135171203240286312343
linear165845380107183783121166192
regression,1866453801072663108133170201232249294340356
while22384538010763109127145183
the2437453801072772111
dashed2564453801074590120165203249
line282945380107193783121
is2966453801071948
the3031453801072672110
line315745380107193783121
of3294453801074568
identity3379453801071863102148173191217256
(y3651453801072459
=37264538010754
x).379645380107376073
R38854538010744
=39454538010753
Pearson’s4015453801074279124150181225272285314
R43464538010743
(A)1841605001122887115
(B)3698605001122882109
(C)5403605001122880109
(D)1841759301122888115
(E)3698759301122876104
(F)5403759301122875103
ORIGINÁLNÍ4694208012673138172244278352422476549582
PRÁCE5297208012661125197257315
COMPARISON106833401063272127163200237255289330373
OF145633401064072
MW\PHARM1544334010654113143177219260296352
3.3019113340106344983117
(DOS)204333401062463105138163
AND222233401063981122
MW\PHARM2359334010654114143178219260297352
++2727334010655110
(WINDOWS)285233401062484103145185227287321345
VERSIONS321333401063870107142160202244278
OF350633401064072
PHARMACOKINETIC359433401063576117153209250285324361380422455489508543
SOFTWARE415333401063274106141203241277310
FOR447933401063072109
PK/PD460433401063471100135175
MODELLING479533401065495136169201233252294335
OF514533401064072
VANCOMYCIN523333401063875117153193248285318337379
IN466344201061557
CONTINUOUS473644201063474116150168210252293336369
ADMINISTRATION512044201064080135153195213247280317360389407449492